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Gene : CORT Homo sapiens

Name  ? cortistatin Cytological Location  1p36.22
Brief Description  cortistatin
Description  This gene encodes a neuropeptide that is structurally similar to somatostatin. It binds to all known somatostatin receptors, and shares many pharmacological and functional properties with somatostatin, including the depression of neuronal activity. However, it also has many properties distinct from somatostatin, such as induction of slow-wave sleep, apparently by antagonism of the excitatory effects of acetylcholine on the cortex, reduction of locomotor activity, and activation of cation selective currents not responsive to somatostatin. The preproprotein undergoes further processing into multiple mature products. Read-through transcripts exist between this gene and the upstream APITD1 (apoptosis-inducing, TAF9-like domain 1) gene, as represented in GeneID:100526739. [provided by RefSeq, Nov 2010]
  • synonyms:
  • CST-14,
  • NM_001302,
  • uc001ari.5,
  • MGC32686,
  • OTTHUMG00000001906,
  • CORT,
  • SST2,
  • HGNC:2257,
  • CST-17,
  • prepro-cortistatin,
  • somatostatin 2,
  • CST-29,
  • AF013252,
  • SST2
  • identifiers:
  • 1325,
  • ENSG00000241563,
  • CORT

Genome feature

Region: gene ? Length: 1968  
Location: 1:10450031-10451998 Cyto location: 1p36.22

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0 Diseases

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436 SNPs

5 Cross References

12 Data Sets

0 Homologues

0 Located Features

97 Rna Seq Results