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Gene : CMBL Homo sapiens

Name  ? carboxymethylenebutenolidase homolog Cytological Location  5p15.2
Brief Description  carboxymethylenebutenolidase homolog
Description  CMBL (EC 3.1.1.45) is a cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL preferentially cleaves cyclic esters, and it activates medoxomil-ester prodrugs in which the medoxomil moiety is linked to an oxygen atom (Ishizuka et al., 2010 [PubMed 20177059]).[supplied by OMIM, Apr 2010]
  • synonyms:
  • NM_138809,
  • carboxymethylenebutenolidase-like (Pseudomonas),
  • CMBL,
  • OTTHUMG00000131043,
  • uc003jes.4,
  • carboxymethylenebutenolidase homolog (Pseudomonas),
  • FLJ23617,
  • JS-1,
  • HGNC:25090
  • identifiers:
  • 134147,
  • ENSG00000164237,
  • CMBL

Genome feature

Region: gene ? Length: 30308  
Location: 5:10277595-10307902 reverse strand Cyto location: 5p15.2


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Function

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Gene -> HPO annotation (Human Phenotype Ontology)

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Genomics

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Proteins

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SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Expression

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Other

955 SN Ps

5 Cross References

15 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results