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Gene : COX15 Homo sapiens

Name  ? cytochrome c oxidase assembly homolog COX15 Cytological Location  10q24.2
Brief Description  cytochrome c oxidase assembly homolog COX15
Description  Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be essential for the biogenesis of COX formation and may function in the hydroxylation of heme O, according to the yeast mutant studies. This protein is predicted to contain 5 transmembrane domains localized in the mitochondrial inner membrane. Alternative splicing of this gene generates two transcript variants diverging in the 3' region. [provided by RefSeq, Jul 2008]
  • synonyms:
  • NM_078470,
  • AF044323,
  • COX15,
  • COX15 (yeast) homolog, cytochrome c oxidase assembly protein,
  • MC4DN6,
  • CEMCOX2,
  • HGNC:2263,
  • COX15, cytochrome c oxidase assembly homolog,
  • uc001kqb.5,
  • OTTHUMG00000018893,
  • identifiers:
  • 1355,
  • ENSG00000014919,
  • COX15

Genome feature

Region: gene ? Length: 37839  
Location: 10:99694293-99732131 reverse strand Cyto location: 10q24.2

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1 Diseases

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552 SNPs

5 Cross References

18 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results