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Gene : CPB2 Homo sapiens

Name  ? carboxypeptidase B2 Cytological Location  13q14.13
Brief Description  carboxypeptidase B2
Description  Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
  • synonyms:
  • thrombin-activatable fibrinolysis inhibitor,
  • carboxypeptidase B2 (plasma),
  • carboxypeptidase U,
  • M75106,
  • carboxypeptidase R,
  • OTTHUMG00000016867,
  • plasma carboxypeptidase B,
  • TAFI,
  • CPB2,
  • NM_001872,
  • HGNC:2300,
  • TAFI,
  • carboxypeptidase B2 (plasma, carboxypeptidase U),
  • uc001vaw.4,
  • PCPB,
  • CPU,
  • PCPB,
  • CPU
  • identifiers:
  • 1361,
  • ENSG00000080618,
  • CPB2

Genome feature

Region: gene ? Length: 51968  
Location: 13:46053066-46105033 reverse strand Cyto location: 13q14.13

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97 SN Ps

5 Cross References

16 Data Sets

24 Homologues

0 Located Features

97 Rna Seq Results