help  | about  | cite  | software

Gene : CLDN3 Homo sapiens

Name  ? claudin 3 Cytological Location  7q11.23
Brief Description  claudin 3
Description  Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat. [provided by RefSeq, Jul 2008]
  • synonyms:
  • C7orf1,
  • CPE-receptor 2,
  • uc003tzg.4,
  • ventral prostate.1-like protein,
  • NM_001306,
  • HGNC:2045,
  • AF007189,
  • CPE-R2,
  • Clostridium perfringens enterotoxin receptor 2,
  • CPETR2,
  • claudin-3,
  • CLDN3,
  • CPE-R2,
  • OTTHUMG00000023424,
  • HRVP1,
  • C7orf1,
  • CPETR2,
  • HRVP1,
  • RVP1,
  • RVP1
  • identifiers:
  • 1365,
  • ENSG00000165215,
  • CLDN3

Genome feature

Region: gene ? Length: 1274  
Location: 7:73768997-73770270 reverse strand Cyto location: 7q11.23

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



858 SN Ps

5 Cross References

15 Data Sets

15 Homologues

0 Located Features

97 Rna Seq Results