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Gene : CLDN7 Homo sapiens

Name  ? claudin 7 Cytological Location  17p13.1
Brief Description  claudin 7
Description  This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc.. Alternatively spliced transcript variants encoding different isoforms have been found.[provided by RefSeq, May 2010]
  • synonyms:
  • CLDN7,
  • HGNC:2049,
  • OTTHUMG00000178005,
  • uc002gfn.5,
  • Hs.84359,
  • CPETRL2,
  • claudin-1,
  • CPETRL2,
  • CEPTRL2,
  • NM_001307,
  • Hs.84359,
  • CLDN-7,
  • AJ011497,
  • identifiers:
  • 1366,
  • ENSG00000181885,
  • CLDN7

Genome feature

Region: gene ? Length: 3311  
Location: 17:7259903-7263213 reverse strand Cyto location: 17p13.1

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene Ontology

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3740 SNPs

5 Cross References

17 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results