help  | about  | cite  | software

Gene : CPN1 Homo sapiens

Name  ? carboxypeptidase N subunit 1 Cytological Location  10q24.2
Brief Description  carboxypeptidase N subunit 1
Description  Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits; this gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency. [provided by RefSeq, Jul 2008]
  • synonyms:
  • carboxypeptidase K,
  • lysine carboxypeptidase,
  • carboxypeptidase N, polypeptide 1,
  • anaphylatoxin inactivator,
  • CPN,
  • CPN1,
  • HGNC:2312,
  • OTTHUMG00000018896,
  • arginine carboxypeptidase,
  • NM_001308,
  • kininase I,
  • SCPN,
  • X14329,
  • carboxypeptidase N, polypeptide 1, 50kD,
  • uc001kql.3
  • identifiers:
  • 1369,
  • ENSG00000120054,
  • CPN1

Genome feature

Region: gene ? Length: 39677  
Location: 10:100042193-100081869 reverse strand Cyto location: 10q24.2


Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer

Function

Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

Homologue Displayer

Gene --> Orthologues

Interactions

Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

439 SN Ps

5 Cross References

18 Data Sets

10 Homologues

0 Located Features

97 Rna Seq Results