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Gene : CPN1 Homo sapiens

Name  ? carboxypeptidase N subunit 1 Cytological Location  10q24.2
Brief Description  carboxypeptidase N subunit 1
Description  Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits; this gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency. [provided by RefSeq, Jul 2008]
  • synonyms:
  • CPN,
  • kininase I,
  • anaphylatoxin inactivator,
  • carboxypeptidase N, polypeptide 1, 50kD,
  • NM_001308,
  • arginine carboxypeptidase,
  • uc001kql.3,
  • SCPN,
  • HGNC:2312,
  • CPN1,
  • OTTHUMG00000018896,
  • lysine carboxypeptidase,
  • carboxypeptidase N, polypeptide 1,
  • X14329,
  • carboxypeptidase K
  • identifiers:
  • 1369,
  • ENSG00000120054,
  • CPN1

Genome feature

Region: gene ? Length: 39677  
Location: 10:100042193-100081869 reverse strand Cyto location: 10q24.2

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1 Diseases

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439 SNPs

5 Cross References

18 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results