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Gene : CLDN23 Homo sapiens

Name  ? claudin 23 Cytological Location  8p23.1
Brief Description  claudin 23
Description  This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed in germinal center B-cells, placenta and stomach as well as in colon tumor. This gene is down-regulated in intestinal type gastric cancer. [provided by RefSeq, Aug 2010]
  • synonyms:
  • NM_194284,
  • CLDNL,
  • OTTHUMG00000163674,
  • AK123547,
  • CLDN23,
  • HGNC:17591,
  • CLDNL,
  • hCG1646163,
  • uc003wsi.4
  • identifiers:
  • 137075,
  • ENSG00000253958,
  • CLDN23

Genome feature

Region: gene ? Length: 2160  
Location: 8:8701937-8704096 Cyto location: 8p23.1


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Function

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Gene -> HPO annotation (Human Phenotype Ontology)

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Genomics

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Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

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Other

3753 SN Ps

4 Cross References

13 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results