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Function
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82 Pathways
- Formation of the beta-catenin:TCF transactivating complex,
- Gene expression (Transcription),
- Activation of gene expression by SREBF (SREBP),
- Transcriptional activation of mitochondrial biogenesis,
- NOTCH1 Intracellular Domain Regulates Transcription,
- Signaling by NOTCH3,
- HATs acetylate histones,
- Cytosolic sensors of pathogen-associated DNA ,
- Metabolism of steroids,
- RORA activates gene expression,
- TRAF3-dependent IRF activation pathway,
- Regulation of FOXO transcriptional activity by acetylation,
- Regulation of cholesterol biosynthesis by SREBP (SREBF),
- Cellular response to hypoxia,
- Organelle biogenesis and maintenance,
- Pre-NOTCH Transcription and Translation,
- Notch-HLH transcription pathway,
- Chromatin modifying enzymes,
- RUNX3 regulates NOTCH signaling,
- Cellular responses to external stimuli,
- Post-translational protein modification,
- Transcriptional regulation by RUNX1,
- Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants,
- Immune System,
- TP53 Regulates Transcription of Cell Death Genes,
- C-type lectin receptors (CLRs),
- Signaling by NOTCH1,
- CD209 (DC-SIGN) signaling,
- Cellular responses to stress,
- Activation of anterior HOX genes in hindbrain development during early embryogenesis,
- PPARA activates gene expression,
- Regulation of beta-cell development,
- Metabolism of proteins,
- Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer,
- SUMOylation of transcription cofactors,
- TRAF6 mediated IRF7 activation,
- Metabolism,
- Diseases of signal transduction by growth factor receptors and second messengers,
- TP53 Regulates Transcription of Genes Involved in Cytochrome C Release,
- Activation of HOX genes during differentiation,
- BMAL1:CLOCK,NPAS2 activates circadian gene expression,
- Transcriptional Regulation by TP53,
- Transcriptional regulation of white adipocyte differentiation,
- Pre-NOTCH Expression and Processing,
- ESR-mediated signaling,
- Metabolism of lipids,
- Innate Immune System,
- Attenuation phase,
- Cellular response to heat stress,
- Transcriptional regulation by RUNX3,
- Constitutive Signaling by NOTCH1 PEST Domain Mutants,
- Signaling by NOTCH4,
- NOTCH3 Intracellular Domain Regulates Transcription,
- Chromatin organization,
- Signal Transduction,
- Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells,
- Signaling by WNT,
- Regulation of lipid metabolism by PPARalpha,
- FOXO-mediated transcription,
- Circadian Clock,
- Mitochondrial biogenesis,
- Developmental Biology,
- RNA Polymerase II Transcription,
- Signaling by NOTCH1 PEST Domain Mutants in Cancer,
- DDX58/IFIH1-mediated induction of interferon-alpha/beta,
- SUMOylation,
- LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production,
- Signaling by NOTCH1 in Cancer,
- RUNX1 regulates transcription of genes involved in differentiation of myeloid cells,
- HSF1-dependent transactivation,
- Disease,
- SUMO E3 ligases SUMOylate target proteins,
- FOXO-mediated transcription of cell death genes,
- Activation of the TFAP2 (AP-2) family of transcription factors,
- TCF dependent signaling in response to WNT,
- Signaling by Nuclear Receptors,
- NOTCH4 Intracellular Domain Regulates Transcription,
- Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors,
- Generic Transcription Pathway,
- Estrogen-dependent gene expression,
- Signaling by NOTCH,
- Regulation of gene expression by Hypoxia-inducible Factor
Gene --> GO terms.
Gene -> HPO annotation (Human Phenotype Ontology)
Mouse Gene --> Allele [Phenotype]
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Disease
Gene (Hum OR Rat) --> Mouse Allele (Phenotype)
Gene --> Alleles and Disease (clinVar data)
Gene -> HPO annotation (Human Phenotype Ontology)
Mouse Gene --> Allele [Phenotype]
Other
82 Pathways
- Formation of the beta-catenin:TCF transactivating complex,
- Gene expression (Transcription),
- Activation of gene expression by SREBF (SREBP),
- Transcriptional activation of mitochondrial biogenesis,
- NOTCH1 Intracellular Domain Regulates Transcription,
- Signaling by NOTCH3,
- HATs acetylate histones,
- Cytosolic sensors of pathogen-associated DNA ,
- Metabolism of steroids,
- RORA activates gene expression,
- TRAF3-dependent IRF activation pathway,
- Regulation of FOXO transcriptional activity by acetylation,
- Regulation of cholesterol biosynthesis by SREBP (SREBF),
- Cellular response to hypoxia,
- Organelle biogenesis and maintenance,
- Pre-NOTCH Transcription and Translation,
- Notch-HLH transcription pathway,
- Chromatin modifying enzymes,
- RUNX3 regulates NOTCH signaling,
- Cellular responses to external stimuli,
- Post-translational protein modification,
- Transcriptional regulation by RUNX1,
- Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants,
- Immune System,
- TP53 Regulates Transcription of Cell Death Genes,
- C-type lectin receptors (CLRs),
- Signaling by NOTCH1,
- CD209 (DC-SIGN) signaling,
- Cellular responses to stress,
- Activation of anterior HOX genes in hindbrain development during early embryogenesis,
- PPARA activates gene expression,
- Regulation of beta-cell development,
- Metabolism of proteins,
- Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer,
- SUMOylation of transcription cofactors,
- TRAF6 mediated IRF7 activation,
- Metabolism,
- Diseases of signal transduction by growth factor receptors and second messengers,
- TP53 Regulates Transcription of Genes Involved in Cytochrome C Release,
- Activation of HOX genes during differentiation,
- BMAL1:CLOCK,NPAS2 activates circadian gene expression,
- Transcriptional Regulation by TP53,
- Transcriptional regulation of white adipocyte differentiation,
- Pre-NOTCH Expression and Processing,
- ESR-mediated signaling,
- Metabolism of lipids,
- Innate Immune System,
- Attenuation phase,
- Cellular response to heat stress,
- Transcriptional regulation by RUNX3,
- Constitutive Signaling by NOTCH1 PEST Domain Mutants,
- Signaling by NOTCH4,
- NOTCH3 Intracellular Domain Regulates Transcription,
- Chromatin organization,
- Signal Transduction,
- Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells,
- Signaling by WNT,
- Regulation of lipid metabolism by PPARalpha,
- FOXO-mediated transcription,
- Circadian Clock,
- Mitochondrial biogenesis,
- Developmental Biology,
- RNA Polymerase II Transcription,
- Signaling by NOTCH1 PEST Domain Mutants in Cancer,
- DDX58/IFIH1-mediated induction of interferon-alpha/beta,
- SUMOylation,
- LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production,
- Signaling by NOTCH1 in Cancer,
- RUNX1 regulates transcription of genes involved in differentiation of myeloid cells,
- HSF1-dependent transactivation,
- Disease,
- SUMO E3 ligases SUMOylate target proteins,
- FOXO-mediated transcription of cell death genes,
- Activation of the TFAP2 (AP-2) family of transcription factors,
- TCF dependent signaling in response to WNT,
- Signaling by Nuclear Receptors,
- NOTCH4 Intracellular Domain Regulates Transcription,
- Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors,
- Generic Transcription Pathway,
- Estrogen-dependent gene expression,
- Signaling by NOTCH,
- Regulation of gene expression by Hypoxia-inducible Factor
