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Gene : CRKL Homo sapiens

Name  ? CRK like proto-oncogene, adaptor protein Cytological Location  22q11.21
Brief Description  CRK like proto-oncogene, adaptor protein
Description  This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.[provided by RefSeq, Jan 2009]
  • synonyms:
  • HGNC:2363,
  • OTTHUMG00000150807,
  • NM_005207,
  • CRKL,
  • v-crk avian sarcoma virus CT10 oncogene homolog-like,
  • uc002ztf.2
  • identifiers:
  • 1399,
  • ENSG00000099942,
  • CRKL

Genome feature

Region: gene ? Length: 36341  
Location: 22:20917407-20953747 Cyto location: 22q11.21


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Disease

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575 SN Ps

5 Cross References

17 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results