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Gene : CRY1 Homo sapiens

Name  ? cryptochrome circadian regulator 1 Cytological Location  12q23.3
Brief Description  cryptochrome circadian regulator 1
Description  This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness. [provided by RefSeq, Jan 2014]
  • synonyms:
  • cryptochrome circadian clock 1,
  • PHLL1,
  • PHLL1,
  • NM_004075,
  • BC030519,
  • OTTHUMG00000170005,
  • DSPD,
  • cryptochrome 1 (photolyase-like),
  • HGNC:2384,
  • CRY1,
  • uc001tmi.5
  • identifiers:
  • 1407,
  • ENSG00000008405,
  • CRY1

Genome feature

Region: gene ? Length: 102509  
Location: 12:106991364-107093872 reverse strand Cyto location: 12q23.3

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1 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



1 Pathways

574 SN Ps

5 Cross References

19 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results