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Gene : CRY2 Homo sapiens

Name  ? cryptochrome circadian regulator 2 Cytological Location  11p11.2
Brief Description  cryptochrome circadian regulator 2
Description  This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2014]
  • synonyms:
  • cryptochrome circadian clock 2,
  • NM_021117,
  • cryptochrome 2 (photolyase-like),
  • CRY2,
  • HCRY2,
  • OTTHUMG00000153225,
  • PHLL2,
  • uc010rgn.2,
  • HGNC:2385,
  • AB014558
  • identifiers:
  • 1408,
  • ENSG00000121671,
  • CRY2

Genome feature

Region: gene ? Length: 36127  
Location: 11:45847118-45883244 Cyto location: 11p11.2

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1 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



1 Pathways

179 SN Ps

5 Cross References

17 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results