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Gene : CRYZ Homo sapiens

Name  ? crystallin zeta Cytological Location  1p31.1
Brief Description  crystallin zeta
Description  Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. The former class is also called phylogenetically-restricted crystallins. This gene encodes a taxon-specific crystallin protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family. Unlike other mammalian species, in humans, lens expression is low. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One pseudogene is known to exist. [provided by RefSeq, Sep 2008]
  • synonyms:
  • crystallin, zeta (quinone reductase),
  • uc001dgk.4,
  • NADPH:quinone reductase,
  • HGNC:2419,
  • quinone oxidoreductase,
  • NM_001130042,
  • OTTHUMG00000009620,
  • CRYZ
  • identifiers:
  • 1429,
  • ENSG00000116791,
  • CRYZ

Genome feature

Region: gene ? Length: 27646  
Location: 1:74705470-74733115 reverse strand Cyto location: 1p31.1


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Function

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

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Expression

Gene(s) --> Significant SNPs (GTex data)

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Other

0 Pathways

3740 SN Ps

5 Cross References

17 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results