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Gene : CSE1L Homo sapiens

Name  ? chromosome segregation 1 like Cytological Location  20q13.13
Brief Description  chromosome segregation 1 like
Description  Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
  • synonyms:
  • uc002xty.5,
  • XPO2,
  • CSE1 chromosome segregation 1-like (yeast),
  • cellular apoptosis susceptibility,
  • CSE1,
  • CSE1L,
  • CSE1 chromosome segregation 1 like,
  • U33286,
  • XPO2,
  • HGNC:2431,
  • OTTHUMG00000033046,
  • CAS,
  • CAS,
  • chromosome segregation 1 (yeast homolog)-like,
  • CSE1,
  • NM_001316
  • identifiers:
  • 1434,
  • ENSG00000124207,
  • CSE1L

Genome feature

Region: gene ? Length: 50715  
Location: 20:49046246-49096960 Cyto location: 20q13.13

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

3753 SN Ps

5 Cross References

16 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results