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Gene : CSF2 Homo sapiens

Name  ? colony stimulating factor 2 Cytological Location  5q31.1
Brief Description  colony stimulating factor 2
Description  The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. This gene plays a role in promoting tissue inflammation. Elevated levels of cytokines, including the one produced by this gene, have been detected in SARS-CoV-2 infected patients that develop acute respiratory distress syndrome. Mice deficient in this gene or its receptor develop pulmonary alveolar proteinosis. [provided by RefSeq, Aug 2020]
  • synonyms:
  • NM_000758,
  • uc003kwf.5,
  • granulocyte-macrophage colony stimulating factor,
  • CSF,
  • HGNC:2434,
  • GMCSF,
  • M11734,
  • sargramostim,
  • GM-CSF,
  • CSF2,
  • OTTHUMG00000059637,
  • colony stimulating factor 2 (granulocyte-macrophage),
  • molgramostim,
  • GMCSF
  • identifiers:
  • 1437,
  • ENSG00000164400,
  • CSF2

Genome feature

Region: gene ? Length: 2382  
Location: 5:132073789-132076170 Cyto location: 5q31.1


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5 Cross References

15 Data Sets

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0 Located Features

97 Rna Seq Results