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Gene : CSH2 Homo sapiens

Name  ? chorionic somatomammotropin hormone 2 Cytological Location  17q23.3
Brief Description  chorionic somatomammotropin hormone 2
Description  The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, while the ratio of 1 to 2 increases by term. Structural and expression differences provide avenues for developmental regulation and tissue specificity. [provided by RefSeq, Jul 2008]
  • synonyms:
  • chorionic somatomammotropin B,
  • hCS-B,
  • placental lactogen,
  • CSB,
  • hCS-B,
  • CS-2,
  • V00573,
  • PL,
  • uc002jch.4,
  • HGNC:2441,
  • CSB,
  • NM_020991,
  • CS-2,
  • OTTHUMG00000172283,
  • CSH2,
  • GHB1
  • identifiers:
  • 1443,
  • ENSG00000213218,
  • CSH2

Genome feature

Region: gene ? Length: 1718  
Location: 17:63872012-63873729 reverse strand Cyto location: 17q23.3

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

3740 SNPs

5 Cross References

15 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results