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Gene : EME1 Homo sapiens

Name  ? essential meiotic structure-specific endonuclease 1 Cytological Location  17q21.33
Brief Description  essential meiotic structure-specific endonuclease 1
Description  This gene encodes a protein that complexes with methyl methanesulfonate-sensitive UV-sensitive 81 protein to form an endonuclease complex. The encoded protein interacts with specifc DNA structures including nicked Holliday junctions, 3'-flap structures and aberrant replication fork structures. This protein may be involved in repairing DNA damage and in maintaining genomic stability. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009]
  • synonyms:
  • MMS4L,
  • SLX2A,
  • HGNC:24965,
  • essential meiotic endonuclease 1 homolog 1 (S. pombe),
  • BC016470,
  • SLX2 structure-specific endonuclease subunit homolog A (S. cerevisiae),
  • OTTHUMG00000164974,
  • EME1,
  • uc002iqs.3,
  • SLX2A,
  • MMS4L,
  • FLJ31364,
  • NM_152463
  • identifiers:
  • 146956,
  • ENSG00000154920,
  • EME1

Genome feature

Region: gene ? Length: 8264  
Location: 17:50373220-50381483 Cyto location: 17q21.33


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Function

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

126 SN Ps

5 Cross References

16 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results