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Gene : CSTA Homo sapiens

Name  ? cystatin A Cytological Location  3q21.1
Brief Description  cystatin A
Description  The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens. This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer. [provided by RefSeq, Jul 2008]
  • synonyms:
  • cystatin A (stefin A),
  • OTTHUMG00000159488,
  • stefin A,
  • STF1,
  • HGNC:2481,
  • AREI,
  • NM_005213,
  • STFA,
  • STF1,
  • CSTA,
  • uc003eex.4,
  • PSS4,
  • STFA
  • identifiers:
  • 1475,
  • ENSG00000121552,
  • CSTA

Genome feature

Region: gene ? Length: 16722  
Location: 3:122325248-122341969 Cyto location: 3q21.1


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Gene -> HPO annotation (Human Phenotype Ontology)

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Proteins

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SNPs

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Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

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Expression

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Other

3753 SN Ps

5 Cross References

19 Data Sets

21 Homologues

0 Located Features

97 Rna Seq Results