help  | about  | cite  | software

Gene : CTNNB1 Homo sapiens

Name  ? catenin beta 1 Cytological Location  3p22.1
Brief Description  catenin beta 1
Description  The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]
  • synonyms:
  • catenin (cadherin-associated protein), beta 1 (88kD),
  • CTNNB,
  • EVR7,
  • OTTHUMG00000131393,
  • CTNNB1,
  • uc010hia.2,
  • MRD19,
  • catenin (cadherin-associated protein), beta 1,
  • HGNC:2514,
  • armadillo,
  • armadillo,
  • CTNNB,
  • NM_001098210,
  • X87838,
  • catenin (cadherin-associated protein), beta 1, 88kDa,
  • beta-catenin
  • identifiers:
  • 1499,
  • ENSG00000168036,
  • CTNNB1

Genome feature

Region: gene ? Length: 41024  
Location: 3:41199422-41240445 Cyto location: 3p22.1

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

55 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


7 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



55 Pathways

3740 SN Ps

5 Cross References

19 Data Sets

8 Homologues

0 Located Features

97 Rna Seq Results