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Gene : DUSP18 Homo sapiens

Name  ? dual specificity phosphatase 18 Cytological Location  22q12.2
Brief Description  dual specificity phosphatase 18
Description  Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP18 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009 [PubMed 19228121]).[supplied by OMIM, Dec 2009]
  • synonyms:
  • DUSP20,
  • DUSP18,
  • HGNC:18484,
  • uc021wnv.2,
  • DUSP20,
  • AF461689,
  • DSP18,
  • LMWDSP20,
  • OTTHUMG00000151115,
  • NM_001304794
  • identifiers:
  • 150290,
  • ENSG00000167065,
  • DUSP18

Genome feature

Region: gene ? Length: 15837  
Location: 22:30652051-30667887 reverse strand Cyto location: 22q12.2

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

3753 SN Ps

5 Cross References

14 Data Sets

2 Homologues

0 Located Features

97 Rna Seq Results