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Gene : CTSG Homo sapiens

Name  ? cathepsin G Cytological Location  14q12
Brief Description  cathepsin G
Description  The protein encoded by this gene, a member of the peptidase S1 protein family, is found in azurophil granules of neutrophilic polymorphonuclear leukocytes. The encoded protease has a specificity similar to that of chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation. In addition, the encoded protein is antimicrobial, with bacteriocidal activity against S. aureus and N. gonorrhoeae. Transcript variants utilizing alternative polyadenylation signals exist for this gene. [provided by RefSeq, Sep 2014]
  • synonyms:
  • NM_001911,
  • M16117,
  • CATG,
  • CTSG,
  • OTTHUMG00000140182,
  • CG,
  • CG,
  • uc001wpq.4,
  • HGNC:2532
  • identifiers:
  • 1511,
  • ENSG00000100448,
  • CTSG

Genome feature

Region: gene ? Length: 2733  
Location: 14:24573518-24576250 reverse strand Cyto location: 14q12


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Function

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

883 SN Ps

5 Cross References

18 Data Sets

52 Homologues

0 Located Features

97 Rna Seq Results