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Gene : CX3CR1 Homo sapiens

Name  ? C-X3-C motif chemokine receptor 1 Cytological Location  3p22.2
Brief Description  C-X3-C motif chemokine receptor 1
Description  Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
  • synonyms:
  • V28,
  • CCRL1,
  • CCRL1,
  • GPRV28,
  • BC028078,
  • GPR13,
  • V28,
  • CMKBRL1,
  • HGNC:2558,
  • OTTHUMG00000156249,
  • chemokine (C-X3-C) receptor 1,
  • GPR13,
  • uc021wwb.2,
  • CMKBRL1,
  • CX3CR1,
  • CMKDR1,
  • NM_001337,
  • chemokine (C-X3-C motif) receptor 1,
  • CMKDR1
  • identifiers:
  • 1524,
  • ENSG00000168329,
  • CX3CR1

Genome feature

Region: gene ? Length: 18242  
Location: 3:39263494-39281735 reverse strand Cyto location: 3p22.2

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Gene -> HPO annotation (Human Phenotype Ontology)

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Gene Report --> GWAS hit


3 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3740 SNPs

5 Cross References

18 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results