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Gene : CYBA Homo sapiens

Name  ? cytochrome b-245 alpha chain Cytological Location  16q24.2
Brief Description  cytochrome b-245 alpha chain
Description  Cytochrome b is comprised of a light chain (alpha) and a heavy chain (beta). This gene encodes the light, alpha subunit which has been proposed as a primary component of the microbicidal oxidase system of phagocytes. Mutations in this gene are associated with autosomal recessive chronic granulomatous disease (CGD), that is characterized by the failure of activated phagocytes to generate superoxide, which is important for the microbicidal activity of these cells. [provided by RefSeq, Jul 2008]
  • synonyms:
  • CYBA,
  • NM_000101,
  • cytochrome b-245, alpha polypeptide,
  • OTTHUMG00000173320,
  • p22-PHOX,
  • HGNC:2577,
  • p22-PHOX,
  • uc002flb.5,
  • flavocytochrome b-558 alpha polypeptide
  • identifiers:
  • 1535,
  • ENSG00000051523,
  • CYBA

Genome feature

Region: gene ? Length: 7791  
Location: 16:88643289-88651079 reverse strand Cyto location: 16q24.2


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Function

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Genomics

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Proteins

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SNPs

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Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

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Expression

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Other

3753 SN Ps

5 Cross References

20 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results