help  | about  | cite  | software

Gene : ADRB2 Homo sapiens

Name  ? adrenoceptor beta 2 Cytological Location  5q32
Brief Description  adrenoceptor beta 2
Description  This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This receptor is also a transcription regulator of the alpha-synuclein gene, and together, both genes are believed to be associated with risk of Parkinson's Disease. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity, type 2 diabetes and cardiovascular disease. [provided by RefSeq, Oct 2019]
  • synonyms:
  • BAR,
  • adrenergic, beta-2-, receptor, surface,
  • ADRBR,
  • ADRB2R,
  • NM_000024,
  • ADRB2,
  • B2AR,
  • B2AR,
  • BAR,
  • BETA2AR,
  • OTTHUMG00000129933,
  • uc003lpr.3,
  • adrenoceptor beta 2, surface,
  • ADRB2R,
  • ADRBR,
  • AF022953,
  • HGNC:286
  • identifiers:
  • 154,
  • ENSG00000169252,
  • ADRB2

Genome feature

Region: gene ? Length: 2013  
Location: 5:148826611-148828623 Cyto location: 5q32

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


2 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



344 SNPs

5 Cross References

19 Data Sets

7 Homologues

0 Located Features

97 Rna Seq Results