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Gene : CYP1B1 Homo sapiens

Name  ? cytochrome P450 family 1 subfamily B member 1 Cytological Location  2p22.2
Brief Description  cytochrome P450 family 1 subfamily B member 1
Description  This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid. [provided by RefSeq, Jul 2008]
  • synonyms:
  • NM_000104,
  • CYPIB1,
  • CYP1B1,
  • OTTHUMG00000100970,
  • cytochrome P450, subfamily I (dioxin-inducible), polypeptide 1 (glaucoma 3, primary infantile),
  • HGNC:2597,
  • ASGD6,
  • GLC3A,
  • P4501B1,
  • cytochrome P450, family 1, subfamily B, polypeptide 1,
  • CP1B,
  • GLC3A,
  • U56438,
  • CP1B,
  • uc032njx.2
  • identifiers:
  • 1545,
  • ENSG00000138061,
  • CYP1B1

Genome feature

Region: gene ? Length: 8643  
Location: 2:38067509-38076151 reverse strand Cyto location: 2p22.2

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3 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

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3740 SN Ps

5 Cross References

19 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results