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Gene : AGR3 Homo sapiens

Name  ? anterior gradient 3, protein disulphide isomerase family member Cytological Location  7p21.1
Brief Description  anterior gradient 3, protein disulphide isomerase family member
Description  This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This gene is expressed in ciliated airway epithelial cells and, in mouse, plays a role in ciliary beat frequency in multiciliated cells. This gene is also over-expressed in breast, ovarian, and prostrate cancers. [provided by RefSeq, Dec 2016]
  • synonyms:
  • hAG-3,
  • AY069977,
  • PDIA18,
  • anterior gradient 3 homolog (Xenopus laevis),
  • hAG-3,
  • AGR3,
  • PDIA18,
  • AG3,
  • HGNC:24167,
  • breast cancer membrane protein 11,
  • protein disulfide isomerase family A, member 18,
  • BCMP11,
  • HAG3,
  • HAG3,
  • BCMP11,
  • OTTHUMG00000128411,
  • NM_176813,
  • uc003sts.4,
  • AG-3
  • identifiers:
  • 155465,
  • ENSG00000173467,
  • AGR3

Genome feature

Region: gene ? Length: 27273  
Location: 7:16854711-16881983 reverse strand Cyto location: 7p21.1

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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0 Pathways

473 SNPs

5 Cross References

15 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results