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Gene : CYP2C8 Homo sapiens

Name  ? cytochrome P450 family 2 subfamily C member 8 Cytological Location  10q23.33
Brief Description  cytochrome P450 family 2 subfamily C member 8
Description  This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
  • synonyms:
  • CPC8,
  • HGNC:2622,
  • CYPIIC8,
  • cytochrome P450, family 2, subfamily C, polypeptide 8,
  • CYP2C8DM,
  • CPC8,
  • MP-12/MP-20,
  • NM_000770,
  • cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 8,
  • uc001kkb.4,
  • OTTHUMG00000018804,
  • CYP2C8,
  • M17397
  • identifiers:
  • 1558,
  • ENSG00000138115,
  • CYP2C8

Genome feature

Region: gene ? Length: 32726  
Location: 10:95036772-95069497 reverse strand Cyto location: 10q23.33

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Gene -> HPO annotation (Human Phenotype Ontology)

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1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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3740 SN Ps

5 Cross References

18 Data Sets

44 Homologues

0 Located Features

97 Rna Seq Results