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Gene : CYP2C9 Homo sapiens

Name  ? cytochrome P450 family 2 subfamily C member 9 Cytological Location  10q23.33
Brief Description  cytochrome P450 family 2 subfamily C member 9
Description  This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008]
  • synonyms:
  • P450IIC9,
  • CPC9,
  • uc001kka.5,
  • cytochrome P450, family 2, subfamily C, polypeptide 9,
  • CYP2C9,
  • CYP2C,
  • cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 9,
  • M61855,
  • NM_000771,
  • OTTHUMG00000018805,
  • CYP2C10,
  • HGNC:2623,
  • P450IIC9,
  • CYP2C10,
  • CYPIIC9
  • identifiers:
  • 1559,
  • ENSG00000138109,
  • CYP2C9

Genome feature

Region: gene ? Length: 51434  
Location: 10:94938658-94990091 Cyto location: 10q23.33


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Function

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

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Genomics

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Proteins

Gene --> Proteins.

SNPs

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Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

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Other

3753 SN Ps

5 Cross References

20 Data Sets

58 Homologues

0 Located Features

97 Rna Seq Results