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Gene : CYP2C9 Homo sapiens

Name  ? cytochrome P450 family 2 subfamily C member 9 Cytological Location  10q23.33
Brief Description  cytochrome P450 family 2 subfamily C member 9
Description  This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008]
  • synonyms:
  • CYP2C,
  • P450IIC9,
  • M61855,
  • CYPIIC9,
  • CYP2C10,
  • CPC9,
  • CYP2C10,
  • cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 9,
  • CYP2C9,
  • P450IIC9,
  • HGNC:2623,
  • NM_000771,
  • cytochrome P450, family 2, subfamily C, polypeptide 9,
  • OTTHUMG00000018805,
  • uc001kka.5
  • identifiers:
  • 1559,
  • ENSG00000138109,
  • CYP2C9

Genome feature

Region: gene ? Length: 51434  
Location: 10:94938658-94990091 Cyto location: 10q23.33

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Proteins.


Gene Report --> GWAS hit


1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3740 SNPs

5 Cross References

19 Data Sets

58 Homologues

0 Located Features

97 Rna Seq Results