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Gene : CYP2C18 Homo sapiens

Name  ? cytochrome P450 family 2 subfamily C member 18 Cytological Location  10q23.33
Brief Description  cytochrome P450 family 2 subfamily C member 18
Description  This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum but its specific substrate has not yet been determined. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. An additional gene, CYP2C17, was once thought to exist; however, CYP2C17 is now considered an artefact based on a chimera of CYP2C18 and CYP2C19. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • synonyms:
  • P450IIC17,
  • CYP2C17,
  • cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 18,
  • CPCI,
  • P450-6B/29C,
  • M61853,
  • CYP2C18,
  • uc001kjv.6,
  • CPCI,
  • NM_000772,
  • cytochrome P450, family 2, subfamily C, polypeptide 18,
  • OTTHUMG00000018796,
  • P450IIC17,
  • CYP2C,
  • CYP2C,
  • CYP2C17,
  • HGNC:2620
  • identifiers:
  • 1562,
  • ENSG00000108242,
  • CYP2C18

Genome feature

Region: gene ? Length: 52462  
Location: 10:94683729-94736190 Cyto location: 10q23.33

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

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Gene Ontology

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3753 SN Ps

5 Cross References

17 Data Sets

44 Homologues

0 Located Features

97 Rna Seq Results