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Gene : CYP8B1 Homo sapiens

Name  ? cytochrome P450 family 8 subfamily B member 1 Cytological Location  3p22.1
Brief Description  cytochrome P450 family 8 subfamily B member 1
Description  This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one. The balance between these two steroids determines the relative amounts of cholic acid and chenodeoxycholic acid both of which are secreted in the bile and affect the solubility of cholesterol. This gene is unique among the cytochrome P450 genes in that it is intronless. [provided by RefSeq, Jul 2008]
  • synonyms:
  • HGNC:2653,
  • uc003cmh.4,
  • CYP8B1,
  • AF090318,
  • CYP12,
  • CP8B,
  • cytochrome P450, family 8, subfamily B, polypeptide 1,
  • cytochrome P450, subfamily VIIIB (sterol 12-alpha-hydroxylase), polypeptide 1,
  • NM_004391,
  • OTTHUMG00000133047,
  • CYP12
  • identifiers:
  • 1582,
  • ENSG00000180432,
  • CYP8B1

Genome feature

Region: gene ? Length: 3688  
Location: 3:42872192-42875879 reverse strand Cyto location: 3p22.1


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757 SN Ps

5 Cross References

15 Data Sets

5 Homologues

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97 Rna Seq Results