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Gene : CYP11B1 Homo sapiens

Name  ? cytochrome P450 family 11 subfamily B member 1 Cytological Location  8q24.3
Brief Description  cytochrome P450 family 11 subfamily B member 1
Description  This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008]
  • synonyms:
  • OTTHUMG00000164637,
  • CPN1,
  • CYP11B1,
  • FHI,
  • CYP11B,
  • D16153,
  • cytochrome P450, family 11, subfamily B, polypeptide 1,
  • CPN1,
  • P450C11,
  • steroid 11-beta-monooxygenase,
  • CYP11B,
  • uc003yxi.4,
  • P450C11,
  • NM_000497,
  • FHI,
  • cytochrome P450, subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 1,
  • HGNC:2591
  • identifiers:
  • 1584,
  • ENSG00000160882,
  • CYP11B1

Genome feature

Region: gene ? Length: 7469  
Location: 8:142872357-142879825 reverse strand Cyto location: 8q24.3

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2 Diseases

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47 SNPs

5 Cross References

17 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results