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Gene : CYP11B2 Homo sapiens
Name  ? cytochrome P450 family 11 subfamily B member 2 Cytological Location  8q24.3
Brief Description  cytochrome P450 family 11 subfamily B member 2
Description  This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency. [provided by RefSeq, Jul 2008]
  • synonyms:
  • X54741,
  • OTTHUMG00000160254,
  • CYP11B,
  • CYPXIB2,
  • CYP11B,
  • cytochrome P450, subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 2,
  • cytochrome P450, family 11, subfamily B, polypeptide 2,
  • CPN2,
  • steroid 11-beta-monooxygenase,
  • ALDOS,
  • P-450C18,
  • CYP11BL,
  • HGNC:2592,
  • P450aldo,
  • P450aldo,
  • NM_000498,
  • P450C18,
  • ALDOS,
  • CYP11BL,
  • CYP11B2,
  • uc003yxk.1,
  • CPN2,
  • P-450C18
  • identifiers:
  • 1585,
  • ENSG00000179142,
  • CYP11B2

Genome feature

Region: gene ? Length: 7285  
Location: 8:142910559-142917843 reverse strand Cyto location: 8q24.3


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14 Pathways

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Disease

2 Diseases

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Gene -> HPO annotation (Human Phenotype Ontology)

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Expression

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14 Pathways

0 SN Ps

5 Cross References

17 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results





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