help  | about  | cite  | software

Gene : CYP11B2 Homo sapiens

Name  ? cytochrome P450 family 11 subfamily B member 2 Cytological Location  8q24.3
Brief Description  cytochrome P450 family 11 subfamily B member 2
Description  This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency. [provided by RefSeq, Jul 2008]
  • synonyms:
  • cytochrome P450, family 11, subfamily B, polypeptide 2,
  • P-450C18,
  • uc003yxk.1,
  • CPN2,
  • CYP11BL,
  • CYP11B2,
  • CPN2,
  • P-450C18,
  • P450aldo,
  • CYP11B,
  • CYP11BL,
  • CYPXIB2,
  • P450C18,
  • OTTHUMG00000160254,
  • cytochrome P450, subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 2,
  • P450aldo,
  • X54741,
  • steroid 11-beta-monooxygenase,
  • ALDOS,
  • HGNC:2592,
  • CYP11B,
  • NM_000498,
  • ALDOS
  • identifiers:
  • 1585,
  • ENSG00000179142,
  • CYP11B2

Genome feature

Region: gene ? Length: 7285  
Location: 8:142910559-142917843 reverse strand Cyto location: 8q24.3


Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer

Function

Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

2 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

Homologue Displayer

Interactions

Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

0 SN Ps

5 Cross References

17 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results