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Gene : CYP19A1 Homo sapiens

Name  ? cytochrome P450 family 19 subfamily A member 1 Cytological Location  15q21.2
Brief Description  cytochrome P450 family 19 subfamily A member 1
Description  This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. Alternative promoter use and alternative splicing results in multiple transcript variants that have different tissue specificities. [provided by RefSeq, Dec 2016]
  • synonyms:
  • CYAR,
  • cytochrome P450, subfamily XIX (aromatization of androgens),
  • CPV1,
  • CYP19A1,
  • uc001zza.5,
  • P-450AROM,
  • ARO1,
  • aromatase,
  • D14473,
  • P-450AROM,
  • ARO,
  • OTTHUMG00000131747,
  • NM_000103,
  • CYP19,
  • CYP19,
  • cytochrome P450, family 19, subfamily A, polypeptide 1,
  • HGNC:2594,
  • CYAR,
  • ARO1,
  • CPV1,
  • ARO
  • identifiers:
  • 1588,
  • ENSG00000137869,
  • CYP19A1

Genome feature

Region: gene ? Length: 130540  
Location: 15:51208057-51338596 reverse strand Cyto location: 15q21.2

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2 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

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3740 SN Ps

5 Cross References

19 Data Sets

31 Homologues

0 Located Features

97 Rna Seq Results