help  | about  | cite  | software

Gene : DARS1 Homo sapiens

Name  ? aspartyl-tRNA synthetase 1 Cytological Location  2q21.3
Brief Description  aspartyl-tRNA synthetase 1
Description  This gene encodes a member of a multienzyme complex that functions in mediating the attachment of amino acids to their cognate tRNAs. The encoded protein ligates L-aspartate to tRNA(Asp). Mutations in this gene have been found in patients showing hypomyelination with brainstem and spinal cord involvement and leg spasticity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
  • synonyms:
  • DARS,
  • DARS1,
  • aspartyl-tRNA synthetase,
  • aspartate tRNA ligase 1, cytoplasmic,
  • uc002tux.2,
  • J05032,
  • OTTHUMG00000131741,
  • HGNC:2678,
  • aspRS,
  • HBSL,
  • NM_001349,
  • DARS
  • identifiers:
  • 1615,
  • ENSG00000115866,
  • DARS1

Genome feature

Region: gene ? Length: 79804  
Location: 2:135905881-135985684 reverse strand Cyto location: 2q21.3

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3740 SN Ps

5 Cross References

19 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results