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Gene : DCN Homo sapiens

Name  ? decorin Cytological Location  12q21.33
Brief Description  decorin
Description  This gene encodes a member of the small leucine-rich proteoglycan family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. This protein plays a role in collagen fibril assembly. Binding of this protein to multiple cell surface receptors mediates its role in tumor suppression, including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis. This gene and the related gene biglycan are thought to be the result of a gene duplication. Mutations in this gene are associated with congenital stromal corneal dystrophy in human patients. [provided by RefSeq, Nov 2015]
  • synonyms:
  • PGII,
  • AF138300,
  • SLRR1B,
  • DSPG2,
  • HGNC:2705,
  • NM_133507,
  • PG40,
  • OTTHUMG00000169998,
  • PGS2,
  • uc001tbu.4,
  • DCN,
  • DSPG2,
  • decorin proteoglycan,
  • CSCD,
  • SLRR1B
  • identifiers:
  • 1634,
  • ENSG00000011465,
  • DCN

Genome feature

Region: gene ? Length: 42334  
Location: 12:91140484-91182817 reverse strand Cyto location: 12q21.33

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1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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551 SN Ps

5 Cross References

20 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results