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Gene : DDOST Homo sapiens

Name  ? dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit Cytological Location  1p36.12
Brief Description  dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit
Description  This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia. [provided by RefSeq, Jul 2008]
  • synonyms:
  • dolichyl-diphosphooligosaccharide-protein glycosyltransferase,
  • OKSWcl45,
  • uc001bdo.1,
  • OST,
  • OST48,
  • HGNC:2728,
  • advanced glycation end-product receptor 1,
  • NM_005216,
  • WBP1,
  • D29643,
  • GATD6,
  • OTTHUMG00000002844,
  • DDOST,
  • AGER1,
  • GATD6,
  • KIAA0115,
  • CDG1R,
  • WBP1,
  • oligosaccharyltransferase subunit 48,
  • OST,
  • OST48
  • identifiers:
  • 1650,
  • ENSG00000244038,

Genome feature

Region: gene ? Length: 9593  
Location: 1:20651777-20661369 reverse strand Cyto location: 1p36.12

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1 Diseases

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794 SN Ps

5 Cross References

19 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results