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Gene : DHX8 Homo sapiens

Name  ? DEAH-box helicase 8 Cytological Location  17q21.31
Brief Description  DEAH-box helicase 8
Description  This gene is a member of the DEAH box polypeptide family. The encoded protein contains the DEAH (Asp-Glu-Ala-His) motif which is characteristic of all DEAH box proteins, and is thought to function as an ATP-dependent RNA helicase that regulates the release of spliced mRNAs from spliceosomes prior to their export from the nucleus. This protein may be required for the replication of human immunodeficiency virus type 1 (HIV-1). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
  • synonyms:
  • DHX8,
  • HRH1,
  • uc002idu.2,
  • OTTHUMG00000180883,
  • PRP22,
  • DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 8 (RNA helicase),
  • Dhr2,
  • PRPF22,
  • DDX8,
  • HRH1,
  • D50487,
  • PRPF22,
  • HGNC:2749,
  • NM_001302623,
  • DDX8,
  • DEAH (Asp-Glu-Ala-His) box polypeptide 8,
  • Dhr2,
  • PRP22
  • identifiers:
  • 1659,
  • ENSG00000067596,
  • DHX8

Genome feature

Region: gene ? Length: 60935  
Location: 17:43483865-43544799 Cyto location: 17q21.31

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1 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Proteins.


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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



1 Pathways

3753 SN Ps

5 Cross References

18 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results