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Gene : TLE5 Homo sapiens

Name  ? TLE family member 5, transcriptional modulator Cytological Location  19p13.3
Brief Description  TLE family member 5, transcriptional modulator
Description  The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • synonyms:
  • AK094591,
  • uc002lwy.2,
  • AES-2,
  • GRG5,
  • Grg-5,
  • AES,
  • amino-terminal enhancer of split,
  • AES,
  • NM_198969,
  • GRG,
  • OTTHUMG00000180567,
  • AES-1,
  • GRG5,
  • HGNC:307,
  • TLE5,
  • ESP1
  • identifiers:
  • 166,
  • ENSG00000104964,
  • TLE5

Genome feature

Region: gene ? Length: 10198  
Location: 19:3052910-3063107 reverse strand Cyto location: 19p13.3

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

711 SN Ps

5 Cross References

13 Data Sets

0 Homologues

0 Located Features

97 Rna Seq Results