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Gene : DDX11 Homo sapiens

Name  ? DEAD/H-box helicase 11 Cytological Location  12p11.21
Brief Description  DEAD/H-box helicase 11
Description  DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an enzyme that possesses both ATPase and DNA helicase activities. This gene is a homolog of the yeast CHL1 gene, and may function to maintain chromosome transmission fidelity and genome stability. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
  • synonyms:
  • NM_030653,
  • HGNC:2736,
  • CHLR1,
  • CHL1-like helicase homolog (S. cerevisiae),
  • DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (S.cerevisiae CHL1-like helicase),
  • uc001rjr.2,
  • CHLR1,
  • OTTHUMG00000168435,
  • CHL1,
  • CHL1,
  • DDX11,
  • U75969,
  • DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11,
  • WABS,
  • DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11,
  • KRG2,
  • KRG2,
  • ChlR1,
  • WABS
  • identifiers:
  • 1663,
  • ENSG00000013573,
  • DDX11

Genome feature

Region: gene ? Length: 30940  
Location: 12:31073860-31104799 Cyto location: 12p11.21

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1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

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Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



37865 SN Ps

5 Cross References

18 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results