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Gene : CRISP1 Homo sapiens

Name  ? cysteine rich secretory protein 1 Cytological Location  6p12.3
Brief Description  cysteine rich secretory protein 1
Description  Fertilization consists of a sequence of specific cell-cell interactions culminating in the fusion of the sperm and egg plasma membranes. Recognition, binding, and fusion occur through the interaction of complementary molecules that are localized to specific domains of the sperm and egg plasma membranes. In the sperm, the postacrosomal region or equatorial segment is involved in sperm-egg plasma membrane fusion. The protein encoded by this gene is a member of the cysteine-rich secretory protein (CRISP) family. It is expressed in the epididymis, is secreted into the epididymal lumen, and binds to the postacrosomal region of the sperm head, where it plays a role in sperm-egg fusion. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
  • synonyms:
  • AEGL1,
  • AEGL1,
  • ARP,
  • NM_001131,
  • D38451,
  • HGNC:304,
  • HEL-S-57,
  • ARP,
  • CRISP1,
  • acidic epididymal glycoprotein-like 1,
  • CRISP-1,
  • CRISP-1,
  • OTTHUMG00000014827,
  • uc021zaj.2
  • identifiers:
  • 167,
  • ENSG00000124812,
  • CRISP1

Genome feature

Region: gene ? Length: 43158  
Location: 6:49833939-49877096 reverse strand Cyto location: 6p12.3

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Proteins.


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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

159 SN Ps

4 Cross References

13 Data Sets

9 Homologues

0 Located Features

97 Rna Seq Results