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Gene : DEFA5 Homo sapiens

Name  ? defensin alpha 5 Cytological Location  8p23.1
Brief Description  defensin alpha 5
Description  Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several of the alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 5, is highly expressed in the secretory granules of Paneth cells of the ileum. [provided by RefSeq, Oct 2014]
  • synonyms:
  • HD-5,
  • DEF5,
  • BC069690,
  • DEF5,
  • HD-5,
  • HGNC:2764,
  • uc003wra.2,
  • OTTHUMG00000090383,
  • DEFA5,
  • NM_021010,
  • defensin, alpha 5, Paneth cell-specific
  • identifiers:
  • 1670,
  • ENSG00000164816,
  • DEFA5

Genome feature

Region: gene ? Length: 1436  
Location: 8:7055304-7056739 reverse strand Cyto location: 8p23.1


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Function

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Gene -> HPO annotation (Human Phenotype Ontology)

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Genomics

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Proteins

Gene --> Proteins.

SNPs

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Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Expression

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Other

28 SN Ps

5 Cross References

16 Data Sets

50 Homologues

0 Located Features

97 Rna Seq Results