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Gene : DEFA6 Homo sapiens

Name  ? defensin alpha 6 Cytological Location  8p23.1
Brief Description  defensin alpha 6
Description  Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 6, is highly expressed in the secretory granules of Paneth cells of the small intestine, and likely plays a role in host defense of human bowel. [provided by RefSeq, Oct 2014]
  • synonyms:
  • M98331,
  • HGNC:2765,
  • defensin, alpha 6, Paneth cell-specific,
  • OTTHUMG00000149984,
  • HD-6,
  • uc003wqt.4,
  • DEF6,
  • NM_001926,
  • DEFA6,
  • DEF6,
  • HD-6
  • identifiers:
  • 1671,
  • ENSG00000164822,
  • DEFA6

Genome feature

Region: gene ? Length: 1380  
Location: 8:6924697-6926076 reverse strand Cyto location: 8p23.1


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Disease

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15 Data Sets

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0 Located Features

97 Rna Seq Results