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Gene : XAGE3 Homo sapiens

Name  ? X antigen family member 3 Cytological Location  Xp11.22
Brief Description  X antigen family member 3
description  This gene is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is expressed in placenta and fetal liver/spleen, and may function in inhibiting cancer cell growth. The protein encoded by this gene shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. Alternative splicing of this gene generates 2 transcript variants differing in the 5' UTR. [provided by RefSeq, Jul 2008]
  • synonyms:
  • GAGED4,
  • pp9012,
  • cancer/testis antigen family 12, member 3a,
  • uc004drf.4,
  • PLAC6,
  • NM_133179,
  • placenta-specific 6; G antigen, family D, 4,
  • pp9012,
  • cancer/testis antigen family 12, member 3b,
  • CT12.3a,
  • CT12.3a,
  • OTTHUMG00000021587,
  • GAGED4,
  • BG354572,
  • XAGE3,
  • X antigen family, member 3,
  • PLAC6,
  • XAGE-3,
  • CT12.3b,
  • CT12.3b,
  • HGNC:14618,
  • XAGE-3
  • identifiers:
  • 170626,
  • ENSG00000171402,
  • XAGE3

Genome feature

Region: gene ? Length: 5613  
Location: X:52862528-52868140 reverse strand Cyto location: Xp11.22

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Orthologues


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

291 SN Ps

5 Cross References

16 Data Sets

25 Homologues

0 Located Features

97 Rna Seq Results