help  | about  | cite  | software

Gene : DHCR24 Homo sapiens

Name  ? 24-dehydrocholesterol reductase Cytological Location  1p32.3
Brief Description  24-dehydrocholesterol reductase
Description  This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells. [provided by RefSeq, Jul 2008]
  • synonyms:
  • DCE,
  • OTTHUMG00000009989,
  • Delta(24)-sterol reductase,
  • seladin-1,
  • desmosterol-to-cholesterol enzyme,
  • seladin-1,
  • KIAA0018,
  • uc001cyc.2,
  • DCE,
  • DHCR24,
  • NM_014762,
  • HGNC:2859,
  • Nbla03646,
  • AF261758
  • identifiers:
  • 1718,
  • ENSG00000116133,
  • DHCR24

Genome feature

Region: gene ? Length: 37569  
Location: 1:54849627-54887195 reverse strand Cyto location: 1p32.3

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3740 SNPs

5 Cross References

19 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results