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Gene : DMBT1 Homo sapiens

Name  ? deleted in malignant brain tumors 1 Cytological Location  10q26.13
Brief Description  deleted in malignant brain tumors 1
Description  Loss of sequences from human chromosome 10q has been associated with the progression of human cancers. This gene was originally isolated based on its deletion in a medulloblastoma cell line. This gene is expressed with transcripts of 6.0, 7.5, and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung, although the 7.5 kb transcript has not been characterized. The encoded protein precursor is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID). Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition. This indicates that DMBT1 may not be a classical tumor suppressor gene, but rather play a role in the interaction of tumor cells and the immune system. [provided by RefSeq, Mar 2016]
  • synonyms:
  • vomeroglandin,
  • salivary agglutinin,
  • hensin,
  • uc057wnp.1,
  • DMBT1,
  • SALSA,
  • muclin,
  • Gp-340,
  • GP340,
  • NM_004406,
  • salivary scavenger and agglutinin,
  • SALSA,
  • OTTHUMG00000019185,
  • muclin,
  • HGNC:2926,
  • GP340,
  • SAG
  • identifiers:
  • 1755,
  • ENSG00000187908,
  • DMBT1

Genome feature

Region: gene ? Length: 83060  
Location: 10:122560677-122643736 Cyto location: 10q26.13


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3753 SN Ps

5 Cross References

17 Data Sets

2 Homologues

0 Located Features

97 Rna Seq Results