help  | about  | cite  | software

Gene : DNM2 Homo sapiens

Name  ? dynamin 2 Cytological Location  19p13.2
Brief Description  dynamin 2
Description  Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined. [provided by RefSeq, Jun 2010]
  • synonyms:
  • DYNII,
  • CMTDIB,
  • CMTDIB,
  • uc002mpu.3,
  • cytoskeletal protein,
  • CMT2M,
  • CMT2M,
  • LCCS5,
  • DI-CMTB,
  • CMTDI1,
  • DYN2,
  • DNM2,
  • DI-CMTB,
  • OTTHUMG00000180694,
  • DYN2,
  • CMTDI1,
  • HGNC:2974,
  • DYNII,
  • NM_004945,
  • dynamin II
  • identifiers:
  • 1785,
  • ENSG00000079805,
  • DNM2

Genome feature

Region: gene ? Length: 113858  
Location: 19:10718053-10831910 Cyto location: 19p13.2


Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer

Function

Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

3 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

Homologue Displayer

Interactions

Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

948 SN Ps

5 Cross References

20 Data Sets

8 Homologues

0 Located Features

97 Rna Seq Results