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Gene : DNM2 Homo sapiens

Name  ? dynamin 2 Cytological Location  19p13.2
Brief Description  dynamin 2
Description  Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined. [provided by RefSeq, Jun 2010]
  • synonyms:
  • DYNII,
  • uc002mpu.3,
  • cytoskeletal protein,
  • CMT2M,
  • CMT2M,
  • LCCS5,
  • DI-CMTB,
  • CMTDI1,
  • DYN2,
  • DNM2,
  • DI-CMTB,
  • OTTHUMG00000180694,
  • DYN2,
  • CMTDI1,
  • HGNC:2974,
  • DYNII,
  • NM_004945,
  • dynamin II
  • identifiers:
  • 1785,
  • ENSG00000079805,
  • DNM2

Genome feature

Region: gene ? Length: 113858  
Location: 19:10718053-10831910 Cyto location: 19p13.2

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3 Diseases

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Gene -> HPO annotation (Human Phenotype Ontology)

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948 SN Ps

5 Cross References

20 Data Sets

8 Homologues

0 Located Features

97 Rna Seq Results