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Gene : DRD4 Homo sapiens

Name  ? dopamine receptor D4 Cytological Location  11p15.5
Brief Description  dopamine receptor D4
Description  This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats. [provided by RefSeq, Jul 2008]
  • synonyms:
  • DRD4,
  • uc001lqp.3,
  • HGNC:3025,
  • NM_000797,
  • L12398,
  • OTTHUMG00000133312,
  • D4DR
  • identifiers:
  • 1815,
  • ENSG00000069696,
  • DRD4

Genome feature

Region: gene ? Length: 3438  
Location: 11:637269-640706 Cyto location: 11p15.5


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Function

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Gene -> HPO annotation (Human Phenotype Ontology)

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Genomics

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Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Expression

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Gene Ontology

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Other

3753 SN Ps

5 Cross References

18 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results