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Gene : E4F1 Homo sapiens

Name  ? E4F transcription factor 1 Cytological Location  16p13.3
Brief Description  E4F transcription factor 1
Description  The zinc finger protein encoded by this gene is one of several cellular transcription factors whose DNA-binding activities are regulated through the action of adenovirus E1A. A 50-kDa amino-terminal product is generated from the full-length protein through proteolytic cleavage. The protein is differentially regulated by E1A-induced phosphorylation. The full-length gene product represses transcription from the E4 promoter in the absence of E1A, while the 50-kDa form acts as a transcriptional activator in its presence. Alternative splicing results in multiple transcripts encoding different proteins. [provided by RefSeq, Jan 2014]
  • synonyms:
  • OTTHUMG00000177084,
  • E4F1,
  • uc002cpm.5,
  • HGNC:3121,
  • E4F,
  • U87269,
  • E4F,
  • NM_004424
  • identifiers:
  • 1877,
  • ENSG00000167967,
  • E4F1

Genome feature

Region: gene ? Length: 12255  
Location: 16:2223488-2235742 Cyto location: 16p13.3

Uni Prot Comments Displayer

Protein Atlas Displayer

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Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

32 SN Ps

5 Cross References

15 Data Sets

2 Homologues

0 Located Features

97 Rna Seq Results