help  | about  | cite  | software

Gene : EFNA1 Homo sapiens

Name  ? ephrin A1 Cytological Location  1q22
Brief Description  ephrin A1
Description  This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin which binds to the EPHA2, EPHA4, EPHA5, EPHA6, and EPHA7 receptors. Two transcript variants that encode different isoforms were identified through sequence analysis. [provided by RefSeq, Jul 2008]
  • synonyms:
  • OTTHUMG00000035312,
  • EPLG1,
  • Tumor necrosis factor alpha-induced protein 4,
  • LERK1,
  • LERK-1,
  • EFL1,
  • NM_004428,
  • TNFAIP4,
  • gastric cancer metastasis associated long noncoding RNA,
  • EFNA1,
  • EPLG1,
  • ECKLG,
  • uc001fhh.4,
  • HGNC:3221,
  • TNFAIP4,
  • B61,
  • LERK1,
  • ECKLG,
  • GMAN,
  • GMAN,
  • ephrin-A1,
  • EPH-related receptor tyrosine kinase ligand 1
  • identifiers:
  • 1942,
  • ENSG00000169242,
  • EFNA1

Genome feature

Region: gene ? Length: 7024  
Location: 1:155127876-155134899 Cyto location: 1q22

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3753 SN Ps

5 Cross References

17 Data Sets

9 Homologues

2 Located Features

97 Rna Seq Results