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Gene : EPHA2 Homo sapiens

Name  ? EPH receptor A2 Cytological Location  1p36.13
Brief Description  EPH receptor A2
Description  This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.[provided by RefSeq, May 2010]
  • synonyms:
  • uc001aya.2,
  • OTTHUMG00000009527,
  • CTPP1,
  • CTRCT6,
  • ECK,
  • BC037166,
  • ARCC2,
  • NM_004431,
  • CTPA,
  • EPHA2,
  • EphA2,
  • ECK,
  • HGNC:3386
  • identifiers:
  • 1969,
  • ENSG00000142627,
  • EPHA2

Genome feature

Region: gene ? Length: 31768  
Location: 1:16124337-16156104 reverse strand Cyto location: 1p36.13

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3753 SN Ps

5 Cross References

18 Data Sets

6 Homologues

1 Located Features

97 Rna Seq Results